Hi @Jfortin1 ,
Thank you for considering adding CRISPRoff score method to the off-target score collection.
I am working with a system that involves paired dCas9 and found free energy based method- CRISPRon score-performs better than other scores. Will you also consider adding this one to your on-target score methods collection? It was developed by the same team as the CRISPRoff package. This one looks pretty straightforward as well.
https://github.com/RTH-tools/crispron
Thank you for considering.
Best
Zhibo
From https://github.com/Jfortin1/crisprScore/issues/6: