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cruizperez / MicrobeAnnotator

Pipeline for metabolic annotation of microbial genomes
Artistic License 2.0
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kofam results are very different with results of local kofamscan or online KofamKOALA #70

Open WangLab-SCSIO opened 1 year ago

WangLab-SCSIO commented 1 year ago

Hi，MicrobeAnnotator is a very useful tool for genome annotation. But I found that kofam results from MicrobeAnnotator are very different (most of them are different) with results of local kofamscan or online KofamKOALA (results of local kofamscan is same with that of online KofamKOALA). Is it caused by different version of kofam database? I found database provided by MicrobeAnnotator (folder: kofam_data) is different from that downloaded from ftp://ftp.genome.jp/pub/db/kofam/. Can I updated the kofam_data manually with the latest kofam database?

marineLZ commented 1 year ago

Just try it.

Yunliang81 commented 1 year ago

My results showed that the size of filtered.fasta by microbeannotator using kofam database is much larger than the filtered.fasta by kofamKOALA (Criteria: assignment score > predefined threshold). It was almost ten times.