search

csbl-usp / CEMiTool

Co-Expression Module Identification Tool (CEMiTool) official repository
21 stars 9 forks source link

Choosing the best diss_thresh #6

Closed thiagodch closed 7 years ago

thiagodch commented 7 years ago

Why is 0.8 the best diss_thresh? The 0.8 gave only 3-4 A/B modules. The higher the value, the less modules are created and more genes per module are present.

pedrostrusso commented 7 years ago

0.8 is the WGCNA default value for module merging by eigengene similarity, so it isn't necessarily the best, just the recommended value by the authors. Nonetheless, we haven't stopped to look for alternative values and/or algorithms, so it will have to do for now.