I think this would be best kept as a separate project you could maintain that uses pyquora and/or the quora-api (so everyone who wants to use quora-api doesn't get them). A few challenges I foresee:
pyquora is currently read-only and doesn't have any write capability yet
Using these lists will only be able to update the statistics on the users already on the lists and won't be able to find new users who have entered their ranks
I'm thinking it would be neat to automatically update the lists on https://www.quora.com/Quora-Usage-Data-and-Analysis/What-Quora-users-have-asked-the-most-questions, https://www.quora.com/Quora-Usage-Data-and-Analysis/What-Quora-users-have-the-most-edits, and https://www.quora.com/Quora-Usage-Data-and-Analysis/What-Quora-users-have-posted-the-highest-number-of-answers. I've done a preliminary extraction of the names given in the wiki answers for each question, which should be a good place to start. Hopefully there aren't any errors. (For the questions list I manually checked, but for the others I just ran the regex and made the items unique (so possibly some problems).)