Fetching information of clinical trials for a specifc disease / gene

Hello,

I would recommend that you use browse_conditions and browser_interventions. Each study has a cluster of MeSH terms associated with it. There is an explanation of this under MeSH Thesaurus on this page https://aact.ctti-clinicaltrials.org/schema. You would have to see if the drug targets are described as MeSH terms, they can get pretty specific.

On Fri, Mar 4, 2022 at 5:33 AM namratasp20 @.***> wrote:

Hi Team,

I have a query pertaining to usage of aact.

I want to pull nct_id for all clinical trials based on disease (eg. any cancer) or pull clinical trials based on drug-gene targets.

Is there a specific way or some correlation to do the same?

Currently, I would need to search in ctgov.conditions for terms like cancer, malignancy, neoplasm, tumor, neoplasia, etc to collect all possible cancer studies. I want to know if there is a way to get this with one search term or maybe some specific column in the database ?

Can it be done similarly for genes ? Eg. Pull all clinical trials where drug target is IDH gene or BRCA gene, etc

Thanks, Namrata

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ctti-clinicaltrials / aact

Fetching information of clinical trials for a specifc disease / gene #923