d3b-center / hope-cohort-analysis

Analysis for HOPE cohort
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generate telomere ratio #67

Closed jharenza closed 12 months ago

jharenza commented 12 months ago

This PR adds a script to generate the telomere ratio from T/N samples using the input file Bo had sent me from the CAVATICA analysis. Per our ALT manuscript and initial validation using c-circle assay, using a cutoff of 1.068 in HGG was highly accurate in determining ALT +/-.