daisybio / drevalpy

DrEval is a toolkit that ensures drug response prediction evaluations are statistically sound, biologically meaningful, and reproducible.
GNU General Public License v3.0
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Visualization #7

Closed PascalIversen closed 4 months ago

PascalIversen commented 6 months ago

For the LCO split, we should add an analysis (R^2 and scatterplot) where we normalize the target by the ground truth drug mean. The remaining variance in the data is then the feature-target associations + noise and not the variance from the different drug means. Thats one way to avoid Simpsons paradox during the analysis.

For the LDO split we can do the same with the cell-line means.

Visualization TODOs: