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dapogon / cellcoal

CellCoal: coalescent simulation of single-cell NGS genotypes
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errors of binary genotype #1

Closed computingmachine closed 3 years ago

computingmachine commented 3 years ago

Hi Dr Posada,

How are the errors added to binary data? For example, I would like to simulate binary data with specified false positive rate 0.1 (G0.1 0.01) and false negative rate 0.01 (-D 0.01). I used the code below but it does not work

bin/cellcoal-1.1.0 -n10 -s10 -l10 -e10000 -g1.0e-04 -k0 -i1 -b0 -j10 -p0.0 -m0 G0.1 0.01 -D 0.01 -1 -2 -3 -4 -5 -6 -9 -v -x -#200011

dapogon commented 3 years ago

Hi,

There was an error in the parsing of -G that prevented its proper used. I fixed and put a new release 1.1.1.

In any case, please note that your command line had a few glitches:

"G0.1 0.01" should be "-G0.1 0.01", and "-D 0.01" should be "-D0.01"

Error generation is explained in the documentation. Best, D