Here we draw a comparison between Minor Allele Frequency and association effect size of the replicated SNPs in our study and the discovery study (CKDGen meta-GWAS; Wuttke et al. 2019).
To do so, we first wrangled the merged GWAS summary files of both studies. For instance we made the effect allele concordant in both studies and turned the effect direction to the positive side in both studies for all variants.
Here we draw a comparison between Minor Allele Frequency and association effect size of the replicated SNPs in our study and the discovery study (CKDGen meta-GWAS; Wuttke et al. 2019).
To do so, we first wrangled the merged GWAS summary files of both studies. For instance we made the effect allele concordant in both studies and turned the effect direction to the positive side in both studies for all variants.