Determine goal of multi-CTSA project

[pnrobinson]

In the original project, we looked at a cohort that was enriched in but not exclusively composed of asthma patients. This type of cohort would be good to have for a larger project.

• [ ] Determine areas of medical interest and opportunity among the chosen CTSA sites
• [ ] Determine method for assigning a patient to a diagnosis or excluding the diagnosis (e.g., ICD codes, or some other means offered by existing CTSA technologies such as OMOP)
• [ ] Analyze our current LOINC2HPO annotations and try to ensure that all tests relevant to the disease of interest as included in our library.
• [ ] If possible, design some test as to whether we are correctly identifying our diagnosis of interest in the cohort, for instance, by manual inspection of 100 charts.

[cgchute]

Manual chart examination is expensive and require another level of IRB, as one would obviously not be dealing with de-id records. It is possible, but would require funds for the reviewers. If you want sensitivity and specificity, you might simply compare with the problem list (as opposed to the billing codes). That would be cheap and scalable.