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davestanley-cogrhythms / A1_delta_gamma_model

DNSim model code for Kramer IB
MIT License
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Testing out jittered RS FS LTS network #2

Open davestanley opened 7 years ago

davestanley commented 7 years ago

Right now, LTS cells do the appropriate behavior on the aperiodic spike based on being driven by noise.

This is because RS cells always fire distinctly ahead of FS cells, which prevents them from properly canceling each other. Due to this lack of cancelation, the most "opportune" firing window is after RS fire and right before FS fire.

I'm going to try to make the RS-FS network more noisy and therefore the spike times will be more jittered and overlapping. Thus, EPSPs and IPSPs from RS and FS cells respectively might be better at cancelling each other out, allowing the "unbalanced" pulse (e.g. the 11th pulse, immediately after the AP pulse) to be the one that triggers LTS firing.

This would be more robust than our current noise-driven LTS firing on the aperiodic pulse.

davestanley commented 7 years ago

Note: I am uniformly increasing Gaussian noise injected to RS, FS, LTS, IB, and NG cells. Left @benpolletta 's cells alone for now. See commit 205830581818693fec99d88285227cecac1375ed

% % Magnitude of injected current Gaussian noise IBda_Vnoise = 6; NG_Vnoise = 6; FS_Vnoise = 6; LTS_Vnoise = 6; RSda_Vnoise = 6; deepRSda_Vnoise = .3; deepFS_Vnoise = 3;

I also finally re-added appropriate gap junctions between LTS cells ggjLTS=.2/Nlts; % LTS -> LTS

See 9015b31d654aab86215a48bbc6ccda05fe82b483