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davidebolo1993 / VISOR

VarIant SimulatOR for short, long and linked reads
GNU Lesser General Public License v3.0
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Add MNP variant type? #10

Closed jasonbwarner closed 4 years ago

jasonbwarner commented 4 years ago

Hi, would you be able to add a new mutation type, MNP, to HACk? The MNP would be such that reference and alternate sequences are of the same length and are greater than 1.

davidebolo1993 commented 4 years ago

Hi @jasonbwarner,

That indeed would be possibile. Would you like to specify the variant sequence in the input BED or should this sequence be generated at random by HACk ?

jasonbwarner commented 4 years ago

Great! I would be specifying the variant sequence in the input BED.

davidebolo1993 commented 4 years ago

Sure. I'll add this as soon as possible, ideally within the next 2 weeks.

Best,

Davide

davidebolo1993 commented 4 years ago

Hi @jasonbwarner,

Just dded MNP variants in VISOR. I've added an example on how to generate a MNP variant in Examples/HACk.bed (last line). I've tested this on a small genome and works just fine. Let me know if I can help further.

Best,

Davide