based on annotator.js, an annotation framework enable user account and annotation permission management and templating annotation plugin in biomedical domain.
Apache License 2.0
4
stars
5
forks
source link
[SPLs import] mark.js missed the sentences to highlight #174
In 5 other schizophrenic patients treated with haloperidol and rifampin, discontinuation of rifampin produced a mean 3.3-fold increase in haloperidol concentrations. Thus, careful monitoring of clinical status is warranted when rifampin is administered or discontinued in haloperidol-treated patients.
Analysis: the div class="Section" is under the ul/li
AND
In a study of 12 schizophrenic patients coadministered haloperidol and rifampin, plasma haloperidol levels were decreased by a mean of 70% and mean scores on the Brief Psychiatric Rating Scale were increased from baseline.
Concomitant administration of propranolol with phenothiazines results in increased plasma levels of both drugs.
Phenothiazines may lower the convulsive threshold; dosage adjustments of anticonvulsants may be necessary. Potentiation of anticonvulsant effects does not occur. However, it has been reported that phenothiazines may interfere with the metabolism of Dilantin®‡ (phenytoin) and thus precipitate Dilantin (phenytoin) toxicity.
Concomitant administration of propranolol with phenothiazines results in increased plasma levels of both drugs
Example 1: http://localhost/DDI-labels/7d1a9689-23c8-44ef-a474-8c607e13d794.html
In 5 other schizophrenic patients treated with haloperidol and rifampin, discontinuation of rifampin produced a mean 3.3-fold increase in haloperidol concentrations. Thus, careful monitoring of clinical status is warranted when rifampin is administered or discontinued in haloperidol-treated patients.
Analysis: the div class="Section" is under the ul/li
AND In a study of 12 schizophrenic patients coadministered haloperidol and rifampin, plasma haloperidol levels were decreased by a mean of 70% and mean scores on the Brief Psychiatric Rating Scale were increased from baseline.
Example 2: http://localhost/DDI-labels/a971ea18-40cf-4a01-b696-180ccc3fddb5.html
Concomitant administration of propranolol with phenothiazines results in increased plasma levels of both drugs.
Phenothiazines may lower the convulsive threshold; dosage adjustments of anticonvulsants may be necessary. Potentiation of anticonvulsant effects does not occur. However, it has been reported that phenothiazines may interfere with the metabolism of Dilantin®‡ (phenytoin) and thus precipitate Dilantin (phenytoin) toxicity.
Concomitant administration of propranolol with phenothiazines results in increased plasma levels of both drugs