deeptools / HiCExplorer

HiCExplorer is a powerful and easy to use set of tools to process, normalize and visualize Hi-C data.
https://hicexplorer.readthedocs.org
GNU General Public License v3.0
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hicHyperoptDetectLoops #771

Closed zhanglp996 closed 2 years ago

zhanglp996 commented 2 years ago

Hello! I want use the 'hicHyperoptDetectLoops' command to call loops ,but I don't know what is '--proteinFile'. Can you give me a example? Thanks for your help.

joachimwolff commented 2 years ago

It's a file containing the information where proteins are located, for example ChIP-Seq CTCF data. https://raw.githubusercontent.com/deeptools/HiCExplorer/master/hicexplorer/test/test_data/hicHyperoptDetectLoops/ctcf_sorted.bed However, to just detect loops please use hicDetectLoops. The tool you listed is only for parameter optimisation of hicDetectLoops: https://hicexplorer.readthedocs.io/en/latest/content/tools/hicDetectLoops.html#hicdetectloops