Thanks for creating such a nice tool.
I have a bit of a noobish question - I have MicroC data which I have processed via pairtools but I'm stuck on how to correctly normalize and correct.
I was wondering if I normalize using hicNormalize on a given .cool file, and then use hicCorrectMatrix correct, when I create a .mcool file from the processed .cool, will the other resolutions also be normalized/corrected? I not, how should I go about this?
Any help/clarification is much appreciated.
All the best,
Noura
Hello,
Thanks for creating such a nice tool. I have a bit of a noobish question - I have MicroC data which I have processed via pairtools but I'm stuck on how to correctly normalize and correct. I was wondering if I normalize using hicNormalize on a given .cool file, and then use hicCorrectMatrix correct, when I create a .mcool file from the processed .cool, will the other resolutions also be normalized/corrected? I not, how should I go about this?
Any help/clarification is much appreciated. All the best, Noura