Closed atancoder closed 8 months ago
I'm using the latest version of pyBigWig and the 'sum' stat doesn't seem to work properly. It returns different results than if i were to sum up the values myself.
>>> from pyBigWig import open as open_bigwig >>> import pyBigWig >>> pyBigWig.__version__ '0.3.22' >>> f = '/oak/stanford/groups/engreitz/Users/atan5133/atac_to_dnase/input_data/DNase.bigwig' >>> bw = open_bigwig(f) >>> bw.stats('chr1', 3774743, 3775877, type='sum') [10.811250448226929] >>> sum(bw.values('chr1', 3774743, 3775877)) 6294.481561243534 >>> bw.stats('chr1', 3774743, 3775877, type='max') [12.645500183105469] >>> max(bw.values('chr1', 3774743, 3775877)) 12.645500183105469
max works as expected. Am I misunderstanding how sum is supposed to work here?
max
edit: perhaps it's due to https://github.com/deeptools/pyBigWig?tab=readme-ov-file#a-note-on-statistics-and-zoom-levels ? But weird how the approximation is quite off
I'm using the latest version of pyBigWig and the 'sum' stat doesn't seem to work properly. It returns different results than if i were to sum up the values myself.
max
works as expected. Am I misunderstanding how sum is supposed to work here?edit: perhaps it's due to https://github.com/deeptools/pyBigWig?tab=readme-ov-file#a-note-on-statistics-and-zoom-levels ? But weird how the approximation is quite off