Open YusenYe opened 6 years ago
Hi,
I have the same question. I guess that the insulationScore in the .insulation.boundaries file may be the insulation strength (not sure), which means the larger the number, the more possible that a bin is a TAD boundary. However, the insulationScore of a bin in the .insulation file is calculated by the mean contacts crossing the current bin, so the boundary is the local minimum of insulationScore.
This is test data's output in your packages.
The output of N2-DpnII10kbchrX.is500001.ids200001.insulation: bin6000201|ce10|chrX:2010001-2020001 2010001 2020001 2015001 201 202 201.5 -0.237082756600542 -0.00117094427035152 -1
The output of N2-DpnII10kbchrX.is500001.ids200001.insulation.boundaries: boundary.3|ce10|chrX:2010001-2020001 2010001 2020001 201 202 201.5 bin6000201|ce10|chrX:2010001-2020001 0.484256934770599
I want to know the difference of insulatioscore between the two files.
Thank you very much! Yusen
I have the same question. So have you figured it out?
This is test data's output in your packages.
The output of N2-DpnII10kbchrX.is500001.ids200001.insulation: bin6000201|ce10|chrX:2010001-2020001 2010001 2020001 2015001 201 202 201.5 -0.237082756600542 -0.00117094427035152 -1
The output of N2-DpnII10kbchrX.is500001.ids200001.insulation.boundaries: boundary.3|ce10|chrX:2010001-2020001 2010001 2020001 201 202 201.5 bin6000201|ce10|chrX:2010001-2020001 0.484256934770599
I want to know the difference of insulatioscore between the two files.
Thank you very much! Yusen