dekoning-lab / slim-tree

4 stars 1 forks source link

Allow user to specify their own ancestral genome and heterogeneous profiles based on profile instead of randomly selecting #2

Closed ebrintn closed 3 years ago

ebrintn commented 3 years ago

This will allow users to run simulations with existing genomes

ebrintn commented 3 years ago

Implemented - but terribly slow - need to find a way to speed up

ebrintn commented 3 years ago

The slowness is an artifact of the number of genes in the genome (with longer genomes it will take longer to run) - we still might want to perform some other optimization

ebrintn commented 3 years ago

There is also a slight problem with population size consistency in the non-wright-fisher models

ebrintn commented 3 years ago

Need to allow user to specify fitness effects and find way to model start and stop codons