Open ceromova opened 1 year ago
Hi,
The consensus sequences are computed by local assembly of all SV-supporting reads. They allow you to examine the SV breakpoint for homology patterns or small insertions.
Best, Tobias
Therefore, if a read is half human genome half viral genome that would be detected by delly and report it as an insertion? This half-half sequence would appear in the consensus sequence?
Thank you.
For long reads, yes.
For short reads, the length of the reads is usually not sufficient and that's why people map against "augmented" references that include the viral sequences.
What do you mean when you say long/short reads? Are you refering to Nanopore as a long read and Illumina as a short read?
Yes.
Hello,
I would like to ask if the consensus sequences of delly's output are human or just unknown insertion sequences (maybe virus or bacteria ones).
Thank you.