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dellytools / delly

DELLY2: Structural variant discovery by integrated paired-end and split-read analysis
BSD 3-Clause "New" or "Revised" License
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Delly on WGBS data #337

Open bounlu opened 1 year ago

bounlu commented 1 year ago

Hi,

I am coming from here.

Basically, Delly is one of the tools suggested to identify SVs from WGBS data.

I am wondering to what extent this is possible. Is Delly aware of methylation at CpG sites?

tobiasrausch commented 1 year ago

Delly only evaluates paired-end mappings. So as long as you used an appropriate mapper for WGBS data it should work but I haven't tested this. Delly is not aware of methylation at CpG sites.