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dellytools / delly

DELLY2: Structural variant discovery by integrated paired-end and split-read analysis
BSD 3-Clause "New" or "Revised" License
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call CNV using a PON #353

Closed lmanchon closed 5 months ago

lmanchon commented 10 months ago

--Hi,

is there a way to call CNVs from a tumor sample using a panel of normal samples and which steps do i need to apply to do that ?

thank you --

tobiasrausch commented 5 months ago

delly cnv adjusts for mappability and GC content in a single (tumor) sample. The method itself does not require a panel of normal.