Question about Algorithm Updates in Delly V2

dellytools / delly

DELLY2: Structural variant discovery by integrated paired-end and split-read analysis

BSD 3-Clause "New" or "Revised" License

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Question about Algorithm Updates in Delly V2 #359

Open ipstone opened 6 months ago

ipstone commented 6 months ago

Hello,

I've been really impressed with how Delly has been maintained and updated over the years. I have two questions regarding the latest version:

Were there any significant algorithmic changes in Delly from the previous versions to version two?
Is there updated documentation or a reference paper for Delly version two that details these changes?

Thanks for your hard work on Delly. Looking forward to your response.

Best, Isaac

tobiasrausch commented 6 months ago

Thanks. Compared to the original publication, Delly has actually changed significantly. The latest changes are mainly related to long read SV calling. I'm afraid that at the moment the only documentation is the software code, but I hope to have some time next year to write a follow-up article on long-read and pan-genome SV calling with Delly.