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dhimmel / integrate

Scripts and resources to create Hetionet v1.0, a heterogeneous network for drug repurposing
https://doi.org/10.15363/thinklab.4
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Add AEOLUS to hetnet #16

Open yhao-compbio opened 5 years ago

yhao-compbio commented 5 years ago

AEOLUS provides a curated and standardized version of FAERS. It

The paper can be accessed at https://doi.org/10.1038/sdata.2016.26

dhimmel commented 5 years ago

Thanks @yhao-compbio for the heads up. I believe I met with some of the authors while this was resource was in preparation, but it came out too late to be incorporated into Hetionet v1.0.

Compared to SIDER which extract side effects from drug labels, the FAERS data should give a better estimate of what extent each compound causes each side effect. This could help us score each side effect or provide a minimum effect size / significance score at which to create a relationship.

Will look into this more if / when we update Hetionet. Also feel free to post any other side effect resources that may be useful.