dieterich-lab / DCC

DCC uses output from the STAR read mapper to systematically detect back-splice junctions in next-generation sequencing data. DCC applies a series of filters and integrates data across replicate sets to arrive at a precise list of circRNA candidates.
https://dieterichlab.org/software/
GNU General Public License v3.0
36 stars 20 forks source link

Check if input BAM files are sorted by coordinate #19

Closed tjakobi closed 8 years ago

tjakobi commented 8 years ago

Currently DCC assumes the BAM files are sorted. In case they are not, pysam will eventually crash.

[bam_pileup_core] the input is not sorted (reads out of order) [bam_plp_destroy] memory leak: 1. Continue anyway.