digitalcytometry / cytospace

CytoSPACE: Optimal mapping of scRNA-seq data to spatial transcriptomics data
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Question About Jittered Coordinates in plot_results_bulk_ST_jitter Function #108

Open aboutfanfan opened 1 day ago

aboutfanfan commented 1 day ago

Thank you for providing such a useful package!

I have a question regarding the default visualization in cell_type_assignments_by_spot_jitter.pdf. My data comes from Stereo-seq (bin=50), and I noticed that in your method, each spot is decomposed into multiple cells, which initially share the same coordinates. To display all the cells in cell_type_assignments_by_spot_jitter, you introduce jittered coordinates for visualization purposes.

I would like to ask: how can we ensure that the added jittered coordinates won’t affect downstream cell neighborhood analysis or other spatial analyses?

Thank you for your time and support!