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ding-lab / CharGer

Characterization of Germline variants
https://ding-lab.github.io/CharGer/
GNU General Public License v3.0
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Reference for inheritanceGeneList 20160301_Rahman_KJ_KH_gene_table_CharGer.txt.gz #48

Closed nah2025 closed 4 years ago

nah2025 commented 4 years ago

Hello,

I was looking for the reference for the inheritance gene list.. (20160301_Rahman_KJ_KH_gene_table_CharGer.txt.gz).

I found this paper from 2016 (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4975511/bin/NIHMS69105-supplement-Supplementary_Table_1.xlsx) but it contains fewer genes than the one here: https://github.com/ding-lab/CharGer/tree/7d7d2911b89261fa5dceea6395a5d188a82757f2/PanCanAtlasData

Can the exact reference be shared?

fernanda-rodrigues commented 4 years ago

Hi I apologize for the delay on getting back to you. The list you're referring to contains 152 cancer predisposition genes, i.e. genes that have been reported to carry rare germline predisposition variants associated with cancer. Please refer to our PanCancer germline paper for details on how this list was compiled: https://doi.org/10.1016/j.cell.2018.03.039

Thanks

nah2025 commented 4 years ago

Thanks for the link.