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diogomribeiro / sc_cop

Single cell local gene co-expression project
MIT License
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Could `ShareSeqCoex.py` work in `non`-Share-seq method ? #5

Closed jiangpuxuan closed 1 year ago

jiangpuxuan commented 1 year ago

We truly appreciate your help and CODer.py script, for it discovering many unprecedented features of our data!

I have both an scRNA-seq and scATAC-seq data for one same kind of biological sample. Differing from Share-seq, cells in my bi-omics data cannot correspond. Could I use ShareSeqCoex.py in my data? Thank you for your help!

diogomribeiro commented 1 year ago

Thank you. ShareSeqCoex.py matches scRNA-seq and scATAC-seq on the same cells, given by a tag (barcode). If no correspondance is given, it will not work. I think there are several methods available to match scRNA-seq and scATAC-seq profiles from different cell pools. Cheers, Diogo

jiangpuxuan commented 1 year ago

Thank you for your advice!