dipetkov / eems

Estimating Effective Migration Surfaces
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Question about the nSites parameter #34

Open SiyangLiu opened 5 years ago

SiyangLiu commented 5 years ago

Dear Desislava, I would like to ask what the "nSites" parameter will be used for? image Based on the above formula in the instruction Manual(Formula 1 in the "Observed vs fitted dissimilarities" section), I assume that the genetic dissimilarity matrix was already normalised by the number of Sites. In this case, why you would require an input of nSites in the *.ini files? My genetic dissimilarity matrix was computed using 3 million common SNPs since it is whole genome low-pass sequencing data. I am a bit afraid that such a large nSites will result in erroneous modelling in the default setting. Could you please advise?