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dkoslicki / NCATS

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only 656 out of 1000 drugs are mapped to a target protein #102

Closed saramsey closed 6 years ago

saramsey commented 6 years ago

@zheng-liu computed some statistics on the KG:

Total # of pharos_drug = 1000 Total # of pharos_drug (targeting a protein) = 656

saramsey commented 6 years ago

@dkoslicki wrote:

Example: phenazepam Should we just return "no result" in these cases?

saramsey commented 6 years ago

@zheng-liu ,

Thank you. Can you send me examples of a few proteins that were not mapped to targets?

Can these example drugs' target proteins be found by a regular query of Pharos using their search box?

https://pharos.nih.gov/idg/index

Thanks, Steve

zheng-liu commented 6 years ago

\<id>:180587 UUID: bae038e8-d28c-11e7-939e-0277022df40c description: expanded: true name: clothiapine seed_node_uuid: baceff92-d28c-11e7-939e-0277022df40c

\<id>:180337 UUID: bad3386e-d28c-11e7-939e-0277022df40c description: expanded: true name: latamoxef seed_node_uuid: baceff92-d28c-11e7-939e-0277022df40c

\<id>:180369 UUID: baceff92-d28c-11e7-939e-0277022df40c description: expanded: true name: butylscopolamine seed_node_uuid: baceff92-d28c-11e7-939e-0277022df40c

I queried the pharos database using the these "isolated" pharos_drug examples and did NOT find the entries for them. At the same time, the ones with target proteins can be queried in the pharos database.