Spatial-eXpression-R: Cell type identification (including cell type mixtures) and cell type-specific differential expression for spatial transcriptomics
I tried to remove the bleeding effect using the SpotClean package and generated an adjusted normalized matrix containing non-integer values. I want to use this matrix as the input for the RCTD analysis. Is there a way to modify this within the runRCTD function, or has somebody already tried this?
Hi,
I tried to remove the bleeding effect using the SpotClean package and generated an adjusted normalized matrix containing non-integer values. I want to use this matrix as the input for the RCTD analysis. Is there a way to modify this within the runRCTD function, or has somebody already tried this?
Thank you
Best, Ayu