dms-vep / LASV_Josiah_GP_DMS

Analysis of DMS data on Lassa virus GP using dms-vep-pipeline-3
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some discussion notes from Jesse re antibody selections #6

Closed jbloom closed 7 months ago

jbloom commented 10 months ago

377H: neutralization vs concentration line very flat

89F: looks reasonably good, but does it help to drop highest antibody concentration out on plateau?

2510C: again, are antibody concentrations too high? Does it help to drop highest one? Fairly poor correlations at all but highest concentration.

121F: already dropped highest concentration, maybe looks OK?

256A: again, neutralization has plateaued as function of concentration. Should highest be dropped?

372D: very poor correlations, antibody neutralization plateued.