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dms-vep / RABV_Pasteur_G_DMS

Deep mutational scan of the Rabies Virus Glycoprotein (RABV-G), Pasteur strain
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Expand mutation counting to phylogroup I lyssaviruses #14

Closed Caleb-Carr closed 7 hours ago

Caleb-Carr commented 1 month ago

Currently, all analysis is restricted to rabies viruses. To look at potential pan-lyssavirus analysis, it might be good to include all phylogroup I lyssa viruses. However, expanding outside of phylogroup I probably isn't a good idea because the different viruses become quite diverged from rabies.

Caleb-Carr commented 1 week ago

This issue is a work in progress because it might not be desirable to show all phylogroup I lyssaviruses on the same tree.

arjunaditham commented 7 hours ago

@Caleb-Carr I think you updated this to be just for rabies circulating strains as requested. If so, I can go ahead and close this issue (or you can close it, as well).

Caleb-Carr commented 7 hours ago

Yes, current version is just Rabies viruses. This seems like the best option because there aren't many sequences for other phylogroup I lyssaviruses and they tend to be quite diverged from rabies, which skews antibody escape coloring.