dms-vep / dms-vep-pipeline-3

Pipeline for analyzing deep mutational scanning (DMS) of viral entry proteins (VEPs)
Other
2 stars 0 forks source link

Add single nucleotide accessibility to heatmaps #105

Closed Bernadetadad closed 7 months ago

Bernadetadad commented 9 months ago

Would be good to be able to see which mutations are single-nucleotide accessible on heatmaps. My though would be we could either add a backslash \ across the squares that are single nucleotide accessible (I think Tyler does this) or we could have a toggle that says show only single nucleotide accessible sites 'yes' 'no'.

This requires to have as an input a native VEP sequence. @jbloom if you want to include this in test_example here's a native nuc sequence for Delta https://www.ncbi.nlm.nih.gov/nuccore/MZ009823.1?from=21533&to=25348&report=fasta