dms-vep / dms-vep-pipeline-3

Pipeline for analyzing deep mutational scanning (DMS) of viral entry proteins (VEPs)
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Add single nucleotide accessibility to heatmaps #105

Closed Bernadetadad closed 2 months ago

Bernadetadad commented 4 months ago

Would be good to be able to see which mutations are single-nucleotide accessible on heatmaps. My though would be we could either add a backslash \ across the squares that are single nucleotide accessible (I think Tyler does this) or we could have a toggle that says show only single nucleotide accessible sites 'yes' 'no'.

This requires to have as an input a native VEP sequence. @jbloom if you want to include this in test_example here's a native nuc sequence for Delta https://www.ncbi.nlm.nih.gov/nuccore/MZ009823.1?from=21533&to=25348&report=fasta