Closed brentp closed 3 years ago
@brentp It shouldn't make a difference for chromosome-split WGS data. For WES or panel data, it's helpful to specify to the target regions (if the GVCF aren't already so filtered) to avoid spending a lot of time on sites that are only covered unintentionally.
great. Thanks!
Hi Mike, thanks for the great software. If I have a setup so I am calling glnexus with a single chromosome (* $n samples), do I need to specify the
--bed
argument with the extent of that chromosome for maximum efficiency? or will glnexus split the work correctly on just the chromosome contained in the set of gvcfs? thanks, -Brent