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dpeerlab / spectra

Supervised Pathway DEConvolution of InTerpretable Gene ProgRAms
MIT License
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The meaning of gene weight? #42

Open yizhang-zoey opened 4 months ago

yizhang-zoey commented 4 months ago

I got a factor A whose top50 genes with high gene weight, and a factor B whose top50 genes with low gene weight. Does it mean factor A is of higher quality than factor B？

For example: 

> factor A
CDKN2A     0.325802
BRCA2      0.313171
CDC6       0.300558
RFC4       0.298734
SLC1A4     0.295682
RRM2       0.284938
OXCT1      0.277684
GGH        0.277203
POLD3      0.271817
E2F1       0.271748
> factor B
CDKN2A     0.325802
BRCA2      0.313171
CDC6       0.300558
RFC4       0.298734
SLC1A4     0.295682
RRM2       0.284938
OXCT1      0.277684
GGH        0.277203
POLD3      0.271817
E2F1       0.271748
russellkune commented 3 months ago

Have you tried using the factor importance and information scores? Let me know if that's helpful