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drivenbyentropy / aptasuite

A full-featured bioinformatics software collection for the comprehensive analysis of aptamers in HT-SELEX experiments.
https://drivenbyentropy.github.io/
GNU General Public License v3.0
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change target #67

Closed yazdan59 closed 5 years ago

yazdan59 commented 5 years ago

Dear friends I want to use "new simulated experiment" section, in order to pick some aptamers based on the simulation result. My question is how could I add a new target molecule in order to find best aptamers binding to it? I could not find any sections related to target definition in the opened dialog box. Thanks in advanced.

drivenbyentropy commented 5 years ago

Thank you for your comment.

The simulation feature is meant to accurately simulate the statistical selection properties of a SELEX experiment. It does not take into account any structural properties of the aptamers or the target. In other words, it is not capable of realistically simulating a selection in a molecular dynamics kind of sense. To the best of my knowledge, such software does not exist.