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drostlab / myTAI

Evolutionary Transcriptomics with R
https://drostlab.github.io/myTAI/
GNU General Public License v2.0
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TAI for transcriptomes in different conditions #8

Closed weikai-320722 closed 3 years ago

weikai-320722 commented 3 years ago

Hi,

I know TAI is used to estimate transcriptome age in different stages of development. If it also can be used to estimate age in different conditions, for example in drought, cold. I sequenced 16 samples (8 control sample and 8 drought sample), I calculated TAI in 16 samples, and got perfect results. So, I just want to ask you if TAI is also suitable to evaluate age of different transcriptomes in different conditions.

Thanks,

Kai

HajkD commented 3 years ago

Hi Kai,

Thank you for this great question!

Yes, you can absolutely use TAI for any biological process or stress condition to characterise the evolutionary age of the underlying transcriptome. In fact, in our publication https://academic.oup.com/bioinformatics/article/34/9/1589/4772684 we encourage the use of TAI for any biological process and beyond developmental genetics questions.

I hope this helps and I am happy to hear that myTAI allowed you to obtain exciting results for your research!

Cheers, Hajk

weikai-320722 commented 3 years ago

Thanks Hajk !