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ebi-chebi / ChEBI

Chemical Entities of Biological Interest (ChEBI) is a freely available dictionary of molecular entities focused on ‘small’ chemical compounds.
https://www.ebi.ac.uk/chebi
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vitamin D3 and its derivatives #2755

Closed muthuvenkat closed 8 years ago

muthuvenkat commented 11 years ago

In looking at how we're using vitamin D3 in GO terms, is it worth having a grouping term in ChEBI for vitamin D3 (calciol; CHEBI:27300) and it's structural derivatives (calcidiol; CHEBI:17933 and calcitriol; CHEBI:17823)?

Inactive vitamin D3 (calciol) is hydroxylated at the 25 position to form calcidiol, then subsequently at the 1-position to form the biologically active form of vitamin D3: calcitriol.

vitamin D3s --[isa]calciol; CHEBI:27300 --[isa]calcidiol; CHEBI:17933 --[isa]calcitriol; CHEBI:17823

? Thanks, Becky

Reported by: rfoulger

muthuvenkat commented 11 years ago

Original comment by: G-Owen

muthuvenkat commented 11 years ago

Hi Becky,

Now done. To avoid confustion over the meaning of the 's', I opted for the ChEBI Name
D3 vitamins (CHEBI:73558), with vitamin D3s as a synonym. The entry will become public with the next release of ChEBI, scheduled for Monday 3rd June.

Kind regards, Gareth

Original comment by: G-Owen

muthuvenkat commented 11 years ago

Original comment by: G-Owen