muthuvenkat
commented
10 years ago Done! The structure now shows a carbide(4-) ion at its centre. Generated data (formula, mass, charge, InChI and Smiles) all auto-updated. Definition and new citations added. Updates will appear in the May 2014 release.
Original comment by: mennis
Hi,
iron-sulfur-molybdenum cofactor, or 7Fe-Mo-9S-X-homocitryl cluster (UniProt name).
Several new publications have been published providing new information about the structure of this cluster, and they show that it is not a N atom that bridges the two halfs of the Fe7S9 cluster, but a carbide ion.
Please update the entry to include this new information.
References: Spatzal T, Aksoyoglu M, Zhang L, Andrade SL, Schleicher E, Weber S, Rees DC, Einsle O. Evidence for interstitial carbon in nitrogenase FeMo cofactor. Science. 2011 Nov 18;334(6058):940. doi: 10.1126/science.1214025. PubMed PMID: 22096190;
Lancaster KM, Roemelt M, Ettenhuber P, Hu Y, Ribbe MW, Neese F, Bergmann U, DeBeer S. X-ray emission spectroscopy evidences a central carbon in the nitrogenase iron-molybdenum cofactor. Science. 2011 Nov 18;334(6058):974-7. doi: 10.1126/science.1206445. PubMed PMID: 22096198.
Wiig JA, Lee CC, Hu Y, Ribbe MW. Tracing the Interstitial Carbide of the Nitrogenase Cofactor during Substrate Turnover. J Am Chem Soc. 2013 Mar 22. [Epub ahead of print] PubMed PMID: 23514429.
Wiig JA, Hu Y, Lee CC, Ribbe MW. Radical SAM-dependent carbon insertion into the nitrogenase M-cluster. Science. 2012 Sep 28;337(6102):1672-5. PubMed PMID: 23019652.
/Kristian
Reported by: axelsen