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ebi-chebi / ChEBI

Chemical Entities of Biological Interest (ChEBI) is a freely available dictionary of molecular entities focused on ‘small’ chemical compounds.
https://www.ebi.ac.uk/chebi
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Potentially missing parent for some agonist/blocker terms #4316

Closed paola-scibite closed 1 year ago

paola-scibite commented 1 year ago

Dear CHEBI editors,

On the grounds that 1) membrane transport modulator CHEBI:38632 = "...affects the transport of molecular entities..." 2) antagonist CHEBI:48706 = "...blocks cell receptors..." 3) ligand-gated ion channels (first 2 below) are types of cell receptors => should the following terms have the additional superclass "antagonist":

GABA-gated chloride channel antagonist CHEBI:38999 calcium channel blocker CHEBI:38215 dopaminergic antagonist CHEBI:48561

There might be more, but these were the most evident. Thanks!

Paola

amalik01 commented 1 year ago

Thanks - These have now been classified as antagonists. If you come across any others, please do let us know.

paola-scibite commented 1 year ago

@amalik01 Thank you for addressing this and other ChEBI edits I requested recently.