muthuvenkat
commented
16 years ago Logged In: YES user_id=1174860 Originator: NO
name: locked nucleic acids CHEBI:48010
name: locked nucleic acid residues CHEBI:48011 (no 'is_a' relationship is required; a 'part_of' relationship is sufficient)
name: glycol nucleic acids CHEBI:48015
name: (R)-glycol nucleic acids CHEBI:48016
name: (S)-glycol nucleic acids CHEBI:48017
name: threose nucleic acids CHEBI:48019
name: peptide nucleic acids CHEBI:48021
For release Dec. 19.
Best regards Marcus
Original comment by: mennis
Hello,
The following terms are needed for SO and text mining.
name: locked nucleic acids def: "Nucleic acid polymers where the residues contain 'locked' deoxyribose units and are linked by phosphodiester bonds. The deoxyribose unit conformation is 'locked' by a 2'-C,4'-C-oxymethylene link." [doi:10.1039/a708608c] synonym: "LNA" EXACT [] is_a: CHEBI:33696 ! nucleic acids
name: locked nucleic acid residues def: "Nucleic acid residues that contain 'locked' deoxyribose units." [doi:10.1039/a708608c] synonym: "LNA residues" EXACT [] relationship: part_of <locked nucleic acids>
I can't work out an is_a parentage for this or any other nucleic acid residue terms.
name: glycol nucleic acids def: "Nucleic acid polymers where the residues have an acyclic three-carbon propylene glycol phosphodiester backbone." [doi:10.1021/ja042564z] synonym: "GNA" EXACT [] synonym: "glycerol nucleic acids" EXACT [] is_a: CHEBI:33696 ! nucleic acids
name: (R)-glycol nucleic acids def: "Glycol nucleic acids with an (R) chiral center in the glycol backbone. They can be synthetically derived from (R)-(+)-glycidol." [doi:10.1021/ja042564z] synonym: "(R)-GNA" EXACT [] synonym: "(R)-glycerol nucleic acids" EXACT [] is_a: <glycol nucleic acids>
name: (S)-glycol nucleic acids def: "Glycol nucleic acids with an (S) chiral center in the glycol backbone. They can be synthetically derived from (S)-(-)-glycidol." [doi:10.1021/ja042564z] synonym: "(S)-GNA" EXACT [] synonym: "(S)-glycerol nucleic acids" EXACT [] is_a: <glycol nucleic acids>
name: threose nucleic acids def: "Nucleic acids that have threose instead of ribose or deoxyribose in their sugar-phosphate backbones." [doi:10.1126/science.290.5495.1347] synonym: "TNA" EXACT [] synonym: "(L)-alpha-threofuranosyl nucleic acids" EXACT [] is_a: CHEBI:33696 ! nucleic acids
name: peptide nucleic acids def: "Nucleic acids where the sugar-phosphate backbone has been replaced by a neutral polyamide backbone such as N-(2-aminoethyl)-glycine units." [doi:10.1039/b510405j] synonym: "PNA" EXACT [] is_a: CHEBI:33696 ! nucleic acids
Best wishes, Colin.
Reported by: batchelorc