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edraizen / HistoneDB

Browse all histone sequences by histone varaints
http://www.ncbi.nlm.nih.gov/projects/HistoneDB2.0
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Keys #131

Closed anna-panchenko closed 8 years ago

anna-panchenko commented 8 years ago

Keys are not well defined, i don't think they correspond to exactly 80% ientical or 50% identical columns: Keys: red - 80% identical, blue - 50% identical columns. X-denotes ambiguous positions in consensus sequence

there are also blue columns with "X" in consensus sequence?

molsim commented 8 years ago

I would need an example to check. Technically: two A and two L in an alignment of 4 sequence will give you that. 50% conservation, but you do not know whether to put A or L into consensus.

anna-panchenko commented 8 years ago

how would you color columns which are more than 80% identical?

molsim commented 8 years ago

they will be red. if we have X in the consensus - this means that the identity can not be more than 50 %. However, it can be roughly 50% - then we have it colored in blue.