Error in file(con, "wb") : cannot open the connection

Hi,

I'm using pathfindR to look at enrichment for different gene expression data sets and have not had problems until now.

I'm running the following command:

output_df <- run_pathfindR(input_df.squirrel_32,
                           gene_sets = "GO-BP",
                           p_val_threshold = 0.05,
                           max_to_plot = 10,
                           output_dir = "fold_change_ANOVA/pathfindR_Results_GO-BP.squirrel_DOWN-32")

and I get the following error:

## Testing input
The input looks OK
## Processing input. Converting gene symbols,
          if necessary (and if human gene symbols provided)
Number of genes provided in input: 616
Number of genes in input after p-value filtering: 616
pathfindR cannot handle p values < 1e-13. These were changed to 1e-13
Could not find any interactions for 3 (0.49%) genes in the PIN
Final number of genes in input: 613
## Performing Active Subnetwork Search and Enrichment
## Processing the enrichment results over all iterations
## Annotating involved genes and visualizing enriched terms
Error in file(con, "wb") : cannot open the connectionpolymerase activity                                                                                                                                                                                                          
In addition: Warning message:
In file(con, "wb") :
  cannot open file 'term_visualizations/positive_regulation_of_DNA-directed_DNA_polymerase.png': No such file or directory

Do you have any idea of what could be causing the problem?

Thanks so much, Lucas

egeulgen / pathfindR

Error in file(con, "wb") : cannot open the connection #170