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eggnogdb / eggnog-mapper

Fast genome-wide functional annotation through orthology assignment
http://eggnog-mapper.embl.de
GNU Affero General Public License v3.0
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unknown gene function clarification: S vs - #443

Closed franciscozorrilla closed 1 year ago

franciscozorrilla commented 1 year ago

Some unknown genes are annotated with the S COG category, while other simply have a -. Is there a difference between these two types of unknown genes or are they effectively equivalent?

Cantalapiedra commented 1 year ago

Hi @franciscozorrilla ,

Technically the difference would be that the proteins of the OG (Orthologous Group) are actually annotated as "S", whereas when there is a "-" it is likely that there is no annotation or not "consensus" COG for the OG.

Best, Carlos