Class looks really good! Sorry for taking so long to review.
A few things:
I think you should allow the constructor to override the device's slave address, even if the hardware doesn't support it. You can use an optional argument in the constructor with a default value:
You should note in the comments at the top of the class:
the fact that the I2C peripheral must be pre-configured
the datasheet URL
In the README, you note that you need 10kΩ pull-ups. These can really be anywhere from 1k to 10k, or even greater, especially if you're running at low speed. I usually recommend 4.7kΩ. Your call whether that's worth changing or not; it's not incorrect!
New Si7021 class and readme