search

erhard-lab / gedi

GNU General Public License v3.0
2 stars 1 forks source link

Why is readcount not an integer? #12

Closed ValeriaFam closed 4 months ago

ValeriaFam commented 4 months ago

Hello,

I would like to use GRAND-SLAM in one of my projects and I am trying it now on the mESC data from the GRAND-SLAM paper. It all went right so I obtained the .tsv file but I was wondering why is readcount not an integer? Is it normalize? If the answer is yes, on what?

Thank you in advance

florianerhard commented 4 months ago

Dear ValeriaFam, multimapping reads are counted as fractions (i.e. if there are two mapping locations, both are counted as 0.5). Counts are not normalized. Florian