Explore databases for genomics in Africa

[miquelduranfrigola]

We need to survey the literature in search for African variants.

Things to consider:

• We do have a set of "favourite" ADME genes (~300), available here. These genes have a relatively high importance in PK/PGx and therefore we should prioritize them (if necessary).
• SnpEff already provides population frequencies. For example, in annotating the 1000 Genomes, we are able to extract population frequencies easily. See this dataset for an example.
• Another potentially interesting resource could be the UK Biobank, which has been recently studied in the context of pharmacogenetics McInnes et al 2021.
• We should survey the literature in search for variants that are prevalent in Africa. @AnnaMontaner feel free to add in this thread the literature that you consider to be more interesting in this regard.

[miquelduranfrigola]

I will close this issue for now. Most progress can be found in the pharmacogx-arsa maintained by @AnnaMontaner