etal / cnvkit

Copy number variant detection from targeted DNA sequencing
http://cnvkit.readthedocs.org
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why remove the cluster process in reference command ? #485

Open qingping12 opened 4 years ago

qingping12 commented 4 years ago

why remove the cluster process in reference command ? different cluster should have more power to detect CNV?

etal commented 4 years ago

The --cluster option is newly introduced in CNVkit v.0.9.7b. It's optional, but it should improve normalization and CNV detection under the right circumstances.