etal / cnvkit

Copy number variant detection from targeted DNA sequencing
http://cnvkit.readthedocs.org
Other
520 stars 163 forks source link

call, segmetrics: Filter by Bayesian mixture model #703

Open etal opened 2 years ago

etal commented 2 years ago

See the method in InferCNV: https://github.com/broadinstitute/inferCNV/wiki/Bayesian-Network-Latent-Mixture-Model

This method uses an existing R package, rjags, to perform MCMC simulations. Functions are here and the driver script is here.

Either wrap this method in segmetrics and call, or alternatively, ensure that the output of segmetrics or export (some format) can be used as input to inferCNV to continue filtering and plotting without reprocessing.