I got the copy number of the target gene by the DPCR experience, and the result is 8.
There are 4 normal and 2tumor samples.
I try to use the "batch" script in cnvkit, and I got the copy number of the target gene, it is 3.
I attempt to use cnvkit by simple script, and after using the "--no-edge" and "--no-gc", the result is 10.
I want to know that If I got the result with "--no-edge" and "--no-gc", is the result obtained in this way meaningful？
I got the copy number of the target gene by the DPCR experience, and the result is 8. There are 4 normal and 2tumor samples.
I try to use the "batch" script in cnvkit, and I got the copy number of the target gene, it is 3. I attempt to use cnvkit by simple script, and after using the "--no-edge" and "--no-gc", the result is 10.
I want to know that If I got the result with "--no-edge" and "--no-gc", is the result obtained in this way meaningful？